Work-related effort thrombosis in a millwright: a case report.

Background: Effort thrombosis refers to axillosubclavian vein thrombosis secondary to physical activities of the upper extremity.

Methods: This report describes the clinical presentation of effort thrombosis in a millwright and reviews the literature for occupational reports of this condition.

Results: While there is a paucity of literature reporting an occupational association, work related physical demands on the upper extremity appears to increase the risk of axillosubclavian impingement and thrombosis in certain patients.

Bone manganese as a biomarker of manganese exposure: a feasibility study.

Background: There is a need for a diagnostic tool with the ability to measure cumulative exposure to manganese (Mn) in the workplace. Measuring bone Mn levels with in vivo neutron activation analysis (IVNAA) could serve as a biomarker of past exposure. Bone Mn levels of welders were measured and compared to the levels found in subjects without exposure to the element.

A preliminary study for non-invasive quantification of manganese in human hand bones.

Manganese (Mn) is a nutrient essential for regulating neurological and skeletal functions in the human body, but it is also toxic when humans are excessively exposed to Mn. Blood (or serum/plasma) and other body fluids reflect only the most recent exposure and rapidly return to within normal ranges, even when there has been a temporary excursion in response to exposure. In this context, we have been developing a non-invasive measurement of Mn stored in bone, using in vivo neutron activation analysis.

Theoretical relationship between maximum pore size and toughness in experimental inflammatory arthritis.

Rheumatoid arthritis increases the risk of fracture. In an animal model of inflammatory arthritis, femoral diaphysis had a decreased toughness as well as increased cortical porosity, when compared to normal bone. Based on the hypothesis that stress concentration from the large porous defects reduces the ability of the cortical bone to resist failure, this work determined if the changes observed in porosity could explain the changes observed in toughness.