Protein fractionation of Hibiscus cannabinus (kenaf) seeds, its characterization, and potential use for water treatment.

This study evaluates the coagulation performance of kenaf protein fractions (KPFs) comprising of albumin (AlbKP), globulin (GloKP), prolamin (ProKP), and glutenin (GluKP), in the treatment of high (500 NTU), medium (150 NTU), and low (30 NTU) turbidity water. Based on preliminary experimental results, the study focused on GloKP due to it outperforming the other kenaf coagulation products (KCPs) in all water types tested. The influence of GloKP, both as a primary coagulant and coagulant aid to aluminum sulfate (AS) on organic matter removal, was examined.

Characterisation and performance of three Kenaf coagulation products under different operating conditions.

The Sustainable Development Goal (SDG) 6.1, established by the United Nations General Assembly in 2015, targets universal and equitable access to safe and affordable drinking water for all by 2030. An essential factor in achieving this goal is the harnessing of "green" coagulants - naturally occurring, environmentally friendly materials which are effective coagulants for use in water treatment, with good availability in developing countries, inherent renewable properties and ease of biodegradation.

The lodging of crops by tornadoes.

It is well known that tornadoes passing over fields can cause significant damage to crops, and tornado tracks of fallen, or lodged, crops can extend for many hundreds of metres. An examination of photographic evidence of such events suggests that, at least for low speed EF0/EF1 events, lodging occurs beneath tornadoes primarily due to a strong radial flow (rather than circumferential flow) at the canopy surface. In order to investigate this effect further, a simple model of a tornado has been developed which, whilst fully satisfying the three dimensional Euler equations, models a circumferential flow at the edge of the tornado boundary layer near the ground, which becomes a radial flow as the ground is approached.

Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition.

Janus kinase (JAK) inhibitors have emerged as an effective class of therapies for various inflammatory diseases such as rheumatoid arthritis (RA). JAK inhibitors function intracellularly by modulating the catalytic activity of JAKs and disrupting the receptor-mediated signaling of multiple cytokines and growth factors, including those with pro-inflammatory activity. Understanding the inhibition profiles of different JAK inhibitors, based on the associated cytokine receptors and downstream inflammatory pathways affected, is important to identify the potential mechanisms for observed differences in efficacy and safety.

Combined inhibition of CCR2 and ACE provides added protection against progression of diabetic nephropathy in -deficient mice.

Macrophage-mediated renal injury promotes the development of diabetic nephropathy. Blockade of chemokine (C-C motif) receptor 2 (CCR2) inhibits kidney macrophage accumulation and early glomerular damage in diabetic animals. This study tested early and late interventions with a CCR2 antagonist (CCR2A) in a model of progressive diabetic glomerulosclerosis and determined whether CCR2A provides added benefit over conventional treatment with an angiotensin-converting enzyme inhibitor (ACEi).