Publications by authors named "M W J Stommel"
Article Synopsis
- - The study examined survival scenarios for pancreatic adenocarcinoma (PAC) patients over 16 years, highlighting best-case, typical, and worst-case survival estimates based on data from the Netherlands Cancer Registry.
- - Patients with localized PAC showed statistically significant improvements in best-case and typical survival scenarios, with gains averaging 1.54 and 0.24 months annually, respectively, while those with metastatic PAC experienced smaller but significant improvements.
- - Factors like age, aggressive treatments, and fewer comorbidities were linked to better survival outcomes, suggesting that recent advancements in care may offer hopeful prospects for PAC patients, despite small absolute survival gains.
Article Synopsis
- The study aimed to assess treatment outcomes, overall survival (OS), and factors influencing OS in patients with T1 ampullary cancer, a rare type of gastrointestinal cancer.
- Out of 244 patients with clinical T1 ampullary cancer, 75% underwent surgery, but a significant number were found to have more advanced disease upon further examination.
- The results indicated a stark difference in survival based on disease classification, with poor prognostic factors including higher pathological N classification and poorly differentiated tumors, emphasizing the need for aggressive treatment like pancreatoduodenectomy for T1 cases.
Background: Estimation of beta cell mass is currently restricted to evaluating pancreatic tissue samples, which provides limited information. A non-invasive imaging technique that reliably quantifies beta cell mass enables monitoring of changes of beta cell mass during the progression of diabetes mellitus and may contribute to monitoring of therapy effectiveness. We assessed the specificity of radiolabelled exendin for beta cell mass quantification in humans.
View Article and Find Full Text PDFASO Visual Abstract: Surgical Outcome After Distal Pancreatectomy With and Without Portomesenteric Venous Resection in Patients with Pancreatic Adenocarcinoma : A Transatlantic Evaluation of Patients in North America, Germany, Sweden, and The Netherlands (GAPASURG).
Ann Surg Oncol
December 2024
Objective: To measure the rate of LTS in resected PDAC and determine the association between predictors of OS and LTS.
Summary Background Data: Long-term survival (>5 y, LTS) remains rare in pancreatic ductal adenocarcinoma (PDAC). Multiple predictors of overall survival (OS) are known but their association with LTS remains unclear.