Publications by authors named "M W F M van Duijnhoven"
The diagnosis of ventilator-associated pneumonia (VAP) recurrence in patients with coronavirus disease 2019 (COVID-19) pneumonia is challenging, and the incidence of recurrence is high. This study aimed to investigate the incidence and recurrence of VAP. Furthermore, we investigated the causative microorganisms of VAP and recurrent VAPs in patients with COVID-19.
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- The study aimed to assess if haloperidol, given preventively, could enhance survival rates in critically ill adults prone to delirium, involving 1,789 participants across 21 ICUs in the Netherlands.
- The research found no significant difference in survival rates between the haloperidol (both 1 mg and 2 mg) and placebo groups after 28 days, leading to the early termination of the 1-mg haloperidol group due to lack of effectiveness.
- Additionally, 15 secondary outcomes related to delirium and ICU stay showed no noteworthy differences, indicating that prophylactic haloperidol might not be beneficial for this patient population.
We describe a patient admitted to the intensive care unit with aphasia, which was due to an embolic ischaemic cerebral stroke associated with a previously unknown patent foramen ovale. Eventually, this finding during echocardiography led us to the diagnosis of pancreatic cancer. The thrombotic complications of pancreatic cancer, in combination with a large, patent foramen ovale, support the mechanism of a paradoxical embolism through the patent foramen ovale as the cause of cerebral ischaemic stroke.
View Article and Find Full Text PDFObjectives: To investigate the effect of weekly alefacept monotherapy 15 mg i.m. on epidermal hyperproliferation, keratinization, T-cell subsets and cells expressing NK receptors during 12 weeks of treatment.
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