Publications by authors named "M W Christoffersen"

Article Synopsis
  • Leodice currently has 34 recorded species worldwide, with seven identified along the Brazilian coast.
  • A study conducted in 1981 along the Continental Shelf of Paraíba led to the discovery of three new records and one new species, Leodice ivanildae.
  • This research raises the total number of Leodice species to 37 globally, with nine found in Brazil, and expands the known species in Paraíba from two to six.
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Importance: Transthyretin tetramer destabilization is the rate-limiting step in the development of transthyretin cardiac amyloidosis, an underrecognized contributor to mortality in older adults.

Objective: To test the hypothesis that transthyretin tetramer destabilization is associated with all-cause and cardiovascular mortality in the general population.

Design, Setting, And Participants: In this cohort study including individuals aged 20 to 80 years, genetic data were analyzed from 2 similar prospective studies of the Danish general population, the Copenhagen City Heart Study (CCHS) and the Copenhagen General Population Study (CGPS).

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Article Synopsis
  • Streptococci are common bacterial causes of abortion in mares, often entering the uterus from the lower genital tract.
  • S. ovis, typically linked to sheep diseases, was found in an 8-month-old aborted equine fetus and connected to severe lung and placental infections.
  • The infection likely occurred after a veterinarian unintentionally damaged the cervical mucus plug during a swab procedure, allowing the bacteria to access the uterus.
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Background And Aims: We tested the association of polygenic risk scores (PRS) for low-density lipoprotein cholesterol (LDL-C) and coronary artery disease (CAD) with LDL-C and risk of ischemic heart disease (IHD) in the Danish general population.

Methods: We included a total of 21,485 individuals from the Copenhagen General Population Study and Copenhagen City Heart Study. For everyone, LDL-PRS and CAD-PRS were calculated, each based on >400,000 variants.

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