Publications by authors named "M W Anderson"
Fluorescent reporters for glutamate release and postsynaptic Ca signaling are essential tools for quantifying synapse functional heterogeneity across neurons and circuits. However, leveraging these probes for neuroscience requires scalable experimental frameworks. Here, we devised a high-throughput approach to efficiently collect and analyze hundreds of optical recordings of glutaamate release activity at presynaptic boutons in cultured rat hippocampal neurons.
View Article and Find Full Text PDFWe examined if anxiety/depression, delay discounting (DD), and their interaction were associated with greater A1c levels and reduced medical adherence in adolescents with type 1 diabetes (T1D). Sixty-one adolescents with T1D completed a DD task and an A1c blood test. Adherence was assessed by self-monitoring of blood glucose (SMBG) using glucometer data.
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- The study explores the current practices and attitudes of interstitial lung disease (ILD) clinicians towards improving health-related quality of life (HRQOL) for patients with Hypersensitivity Pneumonitis (HP).
- Nearly all respondents (100%) believe that interventions to enhance HRQOL are essential, but only 5% currently use validated HRQOL assessment tools.
- Most clinicians reported limited knowledge of behavioral interventions, such as peer coaching and cognitive behavioral therapy (CBT), yet a significant majority expressed a desire to educate patients about these methods and reinforce them post-treatment.
Article Synopsis
- Regular investigations into low back injuries (LBIs) in NCAA sports are essential for understanding their causes and improving prevention and rehabilitation efforts.
- The study analyzed data from the NCAA Injury Surveillance Program over a 10-year period, identifying higher injury rates in women's gymnastics and men's tennis, with significant differences in injury rates between competition and practice events.
- Findings revealed that chronic and recurrent LBIs were more common in women's sports, while overall LBI rates were comparable between men's and women's sports; injuries were generally linked to noncontact and overuse incidents.
Memory control deficits in the sleep-deprived human brain.
Proc Natl Acad Sci U S A
January 2025
Sleep disturbances are associated with intrusive memories, but the neurocognitive mechanisms underpinning this relationship are poorly understood. Here, we show that sleep deprivation disrupts prefrontal inhibition of memory retrieval, and that the overnight restoration of this inhibitory mechanism is associated with time spent in rapid eye movement (REM) sleep. The functional impairments arising from sleep deprivation are linked to a behavioral deficit in the ability to downregulate unwanted memories, and coincide with a deterioration of deliberate patterns of self-generated thought.
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