Normalization of blood lactate as early end-point of polytrauma treatment.

Background: The main aim of the early treatment of polytrauma is recovery of patient's physiological functions. The early achievement of therapeutic goals, mainly adequate tissue perfusion and repayment of oxygen debt, are postulated. The aim of the study was to confirm whether blood lactate level as a quantifier of oxygen deficit, as well as normalization of blood lactate level within the first 24 hours, have an impact on the mortality and morbidity of seriously injured patients.

Occurrence of endemic plasmids causing beta-lactam resistance in Enterobacteriaceae in children's university hospital in Munich.

Susceptibility of 62 clinical isolates of Enterobacteriaceae to 15 aminoglycosides, beta-lactams and fluoroquinolones was determined. The isolates originating from 3 intensive care units (neonatal, pediatric, and surgical) and the Department of Infant Internal Medicine of the Children's University Hospital City Center in Munich (Germany) were collected in August 1999, and March and October 2000. Transferability of antibiotic resistance from donors to their E.