Publications by authors named "M Vocanson"
Introduction: T lymphocyte collection is essential for CAR T-cell engineering in refractory hematologic malignancies but needs to be optimised. No guidelines have been established for predicting the amount of T lymphocytes to be collected. The quantity of lymphocytes and especially T cells collected depends on the pre-cytapheresis lymphocyte blood level (pcLBL) and the number of blood volumes (BVs) processed.
View Article and Find Full Text PDFSevere cutaneous adverse reactions to drugs (SCARs) are rare but life-threatening delayed allergies. While they primarily affect the skin, they can also affect internal organs. Accordingly, they present with diverse clinical symptoms that vary not only between SCARs subtypes but also among patients.
View Article and Find Full Text PDFArticle Synopsis
- Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe, rare skin reactions primarily triggered by drugs, leading to significant health risks and complications.
- The review suggests new diagnostic criteria to better identify these conditions and highlights recent research on how specific immune responses and genetic factors contribute to their development.
- It also discusses current and emerging treatment options, including debates on immunosuppressive therapies and new drug developments targeting specific mechanisms involved in SJS/TEN, advocating for a more collaborative approach in medical research to improve patient care.