Publications by authors named "M Vittoria Pinna"

Leptospirosis is a zoonotic infectious disease that significantly impacts animal and public health. Comparative genomics can aid in understanding poorly understood aspects of leptospirosis pathogenesis, including infection mechanisms, antimicrobial resistance, and host interactions across different epidemiological scenarios. This study aimed to compare the genomes of serogroup Icterohaemorrhagiae strains isolated from three host species in a single epidemiological scenario.

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Leptospirosis is a zoonotic disease caused by bacteria, affecting humans and a broad range of wild and domestic animals in diverse epidemiological settings (rural, urban, and wild). The disease's pathogenesis and epidemiology are complex networks not fully elucidated. Epidemiology reflects the One Health integrated approach of environment-animal-human interaction, causing severe illness in humans and animals, with consequent public health burdens.

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The potential applications of block copolymer thin films, utilising their self-assembly capabilities, are enhanced when achieving long-range ordering. In this study we explain the experimental alignment of lamellae under shear flow findings [S. Pujari , 2012, , 5258] and classify the alignment mechanisms based on shear rate and segregation, uncovering similarities to the systems subjected to electric fields, suggesting a common pathway of lamellae orientations.

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Article Synopsis
  • Mitochondrial dysfunction has been noted in bipolar disorder (BD), but its impact on the disorder's origins and treatment response remains under-researched.* -
  • A study comparing mitochondrial DNA copy number (mtDNA-cn) in 89 BD patients and 78 healthy controls found that BD patients had significantly higher mtDNA-cn levels, especially those treated with other mood stabilizers as opposed to lithium.* -
  • The results indicate that while BD may be linked to mitochondrial issues, lithium treatment appears to lower mtDNA-cn levels, suggesting a potential restoration of mitochondrial function that doesn't necessarily correlate with how well patients respond to the medication.*
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