Publications by authors named "M Vismara"
Article Synopsis
- Significant advancements in neuromodulation, like transcranial magnetic stimulation (TMS), aim to treat treatment-resistant depression (TRD), with a focus on evaluating the effectiveness of standard rTMS versus accelerated rTMS (arTMS).
- The study involved 28 TRD patients, comparing outcomes using psychometric assessments at various intervals, and utilized statistical analyses to evaluate the data.
- Results indicated a notable improvement in depressive symptoms, with arTMS showing a superior clinical response and better cost-effectiveness compared to standard rTMS, though additional research is needed for confirmation.
Despite millennia of therapeutic plant use, deliberate exploitation of 's diverse biomedical potential has only recently gained attention. Bioactivity studies focus mainly on cannabidiol (CBD) and tetrahydrocannabinol (THC) with limited information about the broader cannabinome's "minor phytocannabinoids". In this context, our research targeted the synthesis of minor cannabinoids containing a lateral chain with 3 or 4 carbon atoms, focusing on cannabigerol (CBG) and cannabichromene (CBC) analogues.
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- * Out of 307 patients from various psychiatric diagnoses, one-third reported poor adherence, particularly among those with schizophrenia and bipolar disorder.
- * Poor adherence was linked to higher symptom severity, more hospitalizations, and substance use, indicating that these factors can worsen treatment outcomes for patients.
Obsessive Compulsive Disorder (OCD) is listed as one of the top 10 most disabling neuropsychiatric conditions in the world. The neurobiology of OCD has not been completely understood and efforts are needed in order to develop new treatments. Beside the classical neurotransmitter systems and signalling pathways implicated in OCD, the possible involvement of the endocannabinoid system (ECS) has emerged in pathophysiology of OCD.
View Article and Find Full Text PDFIntroduction: Obsessive-compulsive disorder (OCD) is a prevalent and disabling condition characterized by a wide variety of phenotypic expressions. Several studies have reinforced the hypothesis of OCD heterogeneity by proposing subtypes based on predominant symptomatology, course, and comorbidities. Early-onset OCD (EO) could be considered a neurodevelopmental subtype of OCD, with evidence of distinct neurocircuits supporting disease progression.
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