A Novel Compound Heterozygous Mutation in Progressive Familial Intrahepatic Cholestasis (PFIC) 4: A Rare Case Report With Literature Review.

A 12-year-old female, resident of western India, presented with a history of pruritus associated with jaundice for two months. On presentation, she had icterus with mild palpable hepatomegaly. Investigations revealed direct hyperbilirubinemia and elevated transaminases, while gamma-glutamyl transferase levels were normal.

Relationship of skin complexion with gingival tissue color and hyperpigmentation. A multi-ethnic comparative study.

Background And Objective: The most frequently seen intra-oral soft tissue is the gingiva. Most often, it is seen as coral-pink tissue that surrounds the neck of the teeth. Gingiva that encircles the tooth necks and covers the alveolar processes of the jaws is an intra-oral tissue that exhibits biomimetic features.

Whole Exome Sequencing Reveals Novel Candidate Genes in Familial Forms of Glaucomatous Neurodegeneration.

Glaucoma is the largest cause of irreversible blindness with a multifactorial genetic etiology. This study explores novel genes and gene networks in familial forms of primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) to identify rare mutations with high penetrance. Thirty-one samples from nine -negative families (five POAG and four PACG) underwent whole-exome sequencing and analysis.

Leaf Count Aided Novel Framework for Rice ( L.) Genotypes Discrimination in Phenomics: Leveraging Computer Vision and Deep Learning Applications.

Drought is a detrimental factor to gaining higher yields in rice ( L.), especially amid the rising occurrence of drought across the globe. To combat this situation, it is essential to develop novel drought-resilient varieties.

Supplemental Laser for Eyes Treated with Bevacizumab Monotherapy in Severe Retinopathy of Prematurity.

Purpose: To evaluate the safety and efficacy of a deferred laser treatment after intravitreal bevacizumab (IVB) monotherapy in cases of severe retinopathy of prematurity (ROP) infants.

Design: Retrospective study.

Participants: Infants diagnosed with severe ROP, i.