Publications by authors named "M Virginia Gentilini"

Article Synopsis
  • The study evaluates cancer incidence trends from 2008-2017 in Italy among individuals aged 20-49, utilizing data from 20 cancer registries that cover about one-third of the population.
  • Results show that cancer rates were nearly double for women compared to men, particularly due to breast and thyroid cancers, with significant variations in incidence trends across different cancer types.
  • The findings indicate no consistent increase for early-onset cancers in Italy, with rising rates for some cancers offset by declines in others, underscoring the need for preventive measures and careful screening strategies.
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  • * A training session for dairy farm workers was conducted to enhance their understanding of proper milking procedures, focusing on mastitis risk factors and the significance of each step in the milking process.
  • * Results showed a significant increase in knowledge and improvement in milking practices post-training, such as better disinfectant use and reduced inadequate preparation times, which positively influenced udder health and milk quality.
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  • Variations in access to drugs globally make it hard to assess the effectiveness of modern treatments for patients with relapsed and refractory mature T-cell and NK-cell lymphomas in a study of 925 patients.
  • * The study found that relapsed lymphoma patients had better overall survival rates compared to refractory patients after second-line treatment, with several factors identified as predictors of survival.
  • * A new prognostic index (PIRT) categorizes patients based on risk factors into low, intermediate, or high risk, impacting 3-year overall survival rates, and highlights the superior outcomes of novel therapies compared to traditional chemotherapy.
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First-line therapy for patients with extranodal marginal zone lymphoma (EMZL) is not well established, except for eradication therapy for Helicobacter pylori in early gastric MZL. Various regimens, for example, locoregional treatment and systemic chemo-immunotherapy, can be used depending on the site and stage of disease. Single-agent rituximab is a useful approach in the setting of localized, low-intermediate risk EMZL.

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Importance: Despite increased use of antibiotic-loaded bone cement (ALBC) in joint arthroplasty over recent decades, current evidence for prophylactic use of ALBC to reduce risk of periprosthetic joint infection (PJI) is insufficient.

Objective: To compare the rate of revision attributed to PJI following primary total knee arthroplasty (TKA) using ALBC vs plain bone cement.

Design, Setting, And Participants: This international cohort study used data from 14 national or regional joint arthroplasty registries in Australia, Denmark, Finland, Germany, Italy, New Zealand, Norway, Romania, Sweden, Switzerland, the Netherlands, the UK, and the US.

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