Publications by authors named "M Virgilia Soto-Abraham"

Article Synopsis
  • A 29-year-old pregnant woman from Equatorial Guinea experienced severe malaria due to Plasmodium falciparum, leading to complications such as cerebral malaria and acute kidney injury (AKI), necessitating renal replacement therapy and a kidney biopsy.
  • During her hospitalization, various tests confirmed her malaria diagnosis, and she was treated with antimalarial medications while experiencing significant symptoms including hypotension and haematological issues.
  • The kidney biopsy revealed active tubulointerstitial nephritis, and after intensive dialysis, her kidney function improved, allowing for a successful cesarean delivery and subsequent recovery without deterioration in kidney health.*
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: Rejection continues to be the main cause of renal graft loss. Currently, the gold standard for diagnosis is an allograft biopsy; however, because it is time-consuming, costly, and invasive, the pursuit of novel biomarkers has gained interest. Variation in the expressions of miRNAs is currently considered a probable biomarker for the diagnosis of acute rejection.

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The coronavirus disease 2019 (COVID-19) pandemic was devastating worldwide. The introduction of severe acute respiratory syndrome coronavirus 2 vaccination has reduced transmission, hospitalizations, and deaths, with infrequent major side effects. We present the case of a 51-year-old woman with rapidly progressive glomerulonephritis following COVID-19 vaccination with ChAdOx1 (AstraZeneca).

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Background And Objectives: AKI in coronavirus disease 2019 (COVID-19) is associated with higher morbidity and mortality. The objective of this study was to identify the kidney histopathologic characteristics of deceased patients with diagnosis of COVID-19 and evaluate the association between biopsy findings and clinical variables, including AKI severity.

Design, Setting, Participants, & Measurements: Our multicenter, observational study of deceased patients with COVID-19 in three third-level centers in Mexico City evaluated postmortem kidney biopsy by light and electron microscopy analysis in all cases.

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