Publications by authors named "M Vincenot"

Article Synopsis
  • Researchers have developed a method to analyze pain perception using a 2-min constant heat stimulation, moving beyond traditional group mean analysis due to significant individual variability in responses.
  • New trajectory analysis techniques reveal distinct pain response profiles for participants, showing three unique trajectories: delayed peak pain, classic peak pain followed by a steady increase, and extreme responses with sharp fluctuations.
  • The study found that socio-demographic factors, psychological aspects, and endocannabinoid levels, like anandamide, contribute to these diverse response patterns to pain.
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Background: Quantitative sensory tests (QST) are frequently used to explore alterations in somatosensory systems. Static and dynamic QST like pain threshold and temporal summation (TS) and conditioned pain modulation (CPM) are commonly used to evaluate excitatory and inhibitory mechanisms involved in pain processing. The aim of the present study was to document the reliability and the minimal detectable change (MDC) of these dynamic QST measurements using a standardized experimental paradigm.

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Article Synopsis
  • The article explores the use of qualitative and quantitative sensory testing (QQST) to better understand neuropathic pain by merging personal experiences with measurable data.
  • It highlights the importance of identifying signs of sensory abnormalities and standardizing how data is collected to optimize this testing approach.
  • The QQST method is presented as a key part of the Sensory Evaluation Network, which aims to bring together global experts to improve sensory evaluation techniques.
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Kinesiophobia is associated with pain intensity in people suffering from chronic pain. The number of publications highlighting this relationship has increased significantly in recent years, emphasizing the importance of investigating and synthesizing research evidence on this topic. The purpose of this scoping review was to answer the following questions: (1) What types of interventions have been or are currently being studied in randomized controlled trials (RCTs) for the management of kinesiophobia in patients with chronic pain? (2) What chronic pain conditions are targeted by these interventions? (3) What assessment tools for kinesiophobia are used in these interventions? According to the studies reviewed, (1) physical exercise is the most commonly used approach for managing irrational fear of movement, (2) interventions for kinesiophobia have primarily focused on musculoskeletal pain conditions, particularly low back pain and neck pain, and (3) the Tampa Scale of Kinesiophobia is the most commonly used tool for measuring kinesiophobia.

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Quantitative sensory testing is frequently used in research to assess endogenous pain modulation mechanisms, such as Temporal Summation (TS) and Conditioned Pain Modulation (CPM), reflecting excitatory and inhibitory mechanisms, respectively. Numerous studies found that a dysregulation of these mechanisms is associated with chronic pain conditions. In turn, such a patient's "profile" (increased TS and/or weakened CPM) could be used to recommend different pharmacological treatments.

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