Evaluation of the Antidiabetic Potential of Xanthone-Rich Extracts from and .

Despite the existence of various therapeutic approaches, diabetes mellitus and its complications have been an increasing burden of mortality and disability globally. Hence, it is necessary to evaluate the efficacy and safety of medicinal plants to support existing drugs in treating diabetes. Xanthones, the main secondary metabolites found in and , display various biological activities.

Beneficial Effects of Probiotic BGCG11 on Pancreatic and Duodenum Function in Diabetic Rats.

Diabetes mellitus, as a chronic metabolic disorder, significantly impacts the pancreas and among other organs, affects duodenal function. Emerging evidence suggests that probiotics can exert beneficial effects on gut health and metabolism. In our previous research, we evaluated the probiotic BGCG11 primarily for its protective properties against diabetic rats' damaged liver and kidneys.

Liposome Encapsulation Enhances the Antidiabetic Efficacy of Silibinin.

Silibinin has considerable therapeutic potential for the treatment of diabetes through anti-inflammatory, antioxidant, and immunomodulatory properties. However, the therapeutic application of silibinin is quite limited due to its poor bioavailability. In the present study, an attempt was made to improve the antidiabetic efficacy of silibinin by its encapsulation in liposomal vesicles.