Publications by authors named "M Victoria Monsalve"
Objective: The goal of a decompressive craniectomy (DC) or a hinge craniotomy (HC), is to treat intracranial hypertension and reduce mortality. Traditionally, the decompression procedure has been performed with cranial bone removal. However, decompression and repositioning the cranial bone, named HC, has been presented as an alternative for certain cases.
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- Prolonged use of atypical antipsychotics (AAPs) like olanzapine (OLA) and aripiprazole (ARI) is linked to increased cardiovascular disease risk, with effects on mitochondrial function now being studied.
- In experiments with Fao hepatoma cells, ARI showed resistance to oxidative stress but led to higher apoptosis rates, while OLA worsened cell survival when exposed to stress.
- The study reveals that ARI dampens stress signaling and mitochondrial function, while OLA enhances them, helping to clarify the metabolic risks tied to long-term AAP usage.
Article Synopsis
- - The choice of energy substrate, like glucose or galactose, significantly affects the metabolic pathways of cells in culture, particularly in endothelial cells which have low mitochondrial oxidation.
- - Endothelial cells grown in galactose medium exhibit higher mitochondrial oxidative capacity, a more interconnected mitochondrial network, and increased cell-to-cell communication compared to those grown in glucose medium.
- - Galactose culture conditions lead to elevated levels of the redox regulator FOXO3 and reduced levels of Nrf2 in bovine aortic endothelial cells, suggesting that galactose media is better for studying mitochondrial-related processes and redox signaling.
This study evaluated the intestinal effects of alkalinized filtered water in lean and obese adult Zucker rats. For 3 months, 12-week-old rats consumed either tap water or filtered alkalinized tap water from Madrid city. Weight gain was monitored, changes in metabolism were evaluated by indirect calorimetry, and total antioxidant capacity and levels of inflammatory mediators were measured in plasma.
View Article and Find Full Text PDFA hypercaloric fatty diet predisposes an individual to metabolic syndrome and cardiovascular complications. Sirtuin1 (SIRT1) belongs to the class III histone deacetylase family and sustains anabolism, mitochondrial biogenesis, and fat distribution. Epididymal white adipose tissue (eWAT) is involved in inflammation, whilst interscapular brown adipose tissue (iBAT) drives metabolism in obese rodents.
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