Publications by authors named "M Vicki Potts"

Cranioplasty is a common surgical procedure to repair skull defects. Due to cranioplasty's relatively high complication rates, multidisciplinary surgical teams (MSTs) of neurosurgeons and plastic surgeons have been suggested to improve patient outcomes. However, indications for MST remain undefined.

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Cas12a is a next-generation gene editing tool that enables multiplexed gene targeting. Here, we present a mouse model that constitutively expresses enhanced Acidaminococcus sp. Cas12a (enAsCas12a) linked to an mCherry fluorescent reporter.

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Objective: Dolichoectatic vertebrobasilar aneurysms (DVBAs) are expansions of arterial tissue leading to aneurysmal formations without an obvious neck. Their natural history is poorly understood; usually patients are admitted with thromboembolic complications and/or neurological symptoms from the mass effect. There have not been international collective data, and correct timing for highly risky treatments has been under discussion.

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Article Synopsis
  • The study investigates the relationship between body weight and leukopenia in solid organ transplant recipients on valganciclovir (VGC) prophylaxis to prevent cytomegalovirus disease.
  • Over half (52%) of the patients developed leukopenia, with those having a higher starting weight (97.9 kg) less likely to experience it compared to lower-weight patients (90.7 kg).
  • Results indicate that each 1 kg increase in body weight decreases the risk of leukopenia by about 1.7%, highlighting the importance of considering patient weight in VGC dosing.
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