Cranioplasty is a common surgical procedure to repair skull defects. Due to cranioplasty's relatively high complication rates, multidisciplinary surgical teams (MSTs) of neurosurgeons and plastic surgeons have been suggested to improve patient outcomes. However, indications for MST remain undefined.
View Article and Find Full Text PDFCas12a is a next-generation gene editing tool that enables multiplexed gene targeting. Here, we present a mouse model that constitutively expresses enhanced Acidaminococcus sp. Cas12a (enAsCas12a) linked to an mCherry fluorescent reporter.
View Article and Find Full Text PDFObjective: Dolichoectatic vertebrobasilar aneurysms (DVBAs) are expansions of arterial tissue leading to aneurysmal formations without an obvious neck. Their natural history is poorly understood; usually patients are admitted with thromboembolic complications and/or neurological symptoms from the mass effect. There have not been international collective data, and correct timing for highly risky treatments has been under discussion.
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