J Appl Physiol (1985)
January 2025
The influence of peripheral antitussive drugs on spatiotemporal features of coughing has not been reported. We hypothesized that this class of compounds would alter the cough motor pattern, in part, by lengthening cough phases. Peripherally acting antitussives, 3-aminopropylphosphinic acid (3APPi, 5 mg/kg) and levodropropizine (Levo, 3 mg/kg) were injected intravenously in anesthetized spontaneously breathing cats (13 males, 2 females; 4.
View Article and Find Full Text PDFRespir Physiol Neurobiol
November 2024
The relationship between the level (rate) of stimulus and the characteristics of the cough response was studied on 15 spontaneously breathing anesthetized cats. Three modes of stimulation were used to elicit cough. 'High' vs.
View Article and Find Full Text PDFRespir Physiol Neurobiol
December 2024
Codeine was microinjected into the area of the Kölliker-Fuse nucleus and the adjacent lateral parabrachial nucleus, within the pontine respiratory group in 8 anesthetized cats. Electromyograms (EMGs) of the diaphragm (DIA) and abdominal muscles (ABD), esophageal pressures (EP), and blood pressure were recorded and analyzed during mechanically induced tracheobronchial cough. Unilateral microinjections of 3.
View Article and Find Full Text PDFEffects of sequential increase in airway resistance: no, low (5 kPa.s/l), high (24 kPa.s/l), and complete block in the inspiratory or expiratory phase of mechanically induced cough on the cough motor pattern were studied in 16 anesthetized (pentobarbital) spontaneously breathing cats (3.
View Article and Find Full Text PDFUnlabelled: Listening to music is experimentally associated with positive stress reduction effect on human organisms. However, the opinions of therapists about this complementary non-invasive therapy are still different.
Purpose: The aim of our study was to investigate the effect of selected passive music therapy frequencies without vocals on selected cardio-vagal and complexity indices of short-term heart rate variability (HRV) in healthy youth, in terms of calming the human.