Propofol sedation: intensivists' experience with 7304 cases in a children's hospital.

Objective: The objective of this study was to determine the safety profile of propofol as a deep-sedation agent in a primarily outpatient program consisting of pediatric critical care physicians and specifically trained nurses with oversight provided by anesthesiology. One hypothesis was investigated: adverse events and/or airway interventions are more likely to occur in children with an abnormal airway score.

Methods: A 36-month dual-site prospective, observational, clinical study was conducted in a single center with interchangeable providers operating within the guidelines of a single sedation program.

Longitudinal analysis of neutrophil superoxide anion generation in patients with septic shock.

Objective: To examine polymorphonuclear leukocyte respiratory burst function serially in patients with septic shock.

Design: Prospective, longitudinal, descriptive study.

Setting: Adult and pediatric (university hospital) intensive care units.

Olfactory deficits in boys with cleft palate.

An odor identification task was used to determine whether individuals with cleft palate (with or without cleft lip) also have an increased prevalence of olfactory deficits. Olfactory responses of 35 affected subjects (7 to 22 years of age) were compared with those of 68 subjects of comparable age without cleft palates. Subjects were requested to identify the smell of ten common household odors.