Lipid disorder and transplant coronary artery disease in long-term survivors of heart transplantation.

Background: Transplant coronary artery disease is the major cause of late mortality after heart transplantation. The underlying mechanism probably involves various factors including immunologic and nonimmunologic factors.

Methods: The influence of various risk factors concerning both the development and the progression of transplant coronary artery disease was analyzed.

Regression of transplant coronary artery disease during chronic HELP therapy: a case study.

This report concerns a heart transplant patient with hypercholesterolemia who showed rapid development of a severe transplant coronary artery disease. The patient received 10 mg pravastatine per day. Quantitative coronary angiography analyses of 4 serial angiograms clearly demonstrated that in the first 2.