Enantiomeric differentiation of oxygenated p-menthane derivatives by 13C NMR using Yb(hfc)3.

The (13)C NMR behaviour of 21 p-menthanic terpene bearing an oxygenated function (alcohol, ketone, acetate) was examined in the presence of a chiral lanthanide shift reagent (Yb(hfc)(3)). For each monocyclic compound, we measured the lanthanide-induced shift (LIS) on the signals of the carbons and the splitting of signals allowing the enantiomeric differentiation. Some general features were found about their LIS behaviour: experimental data establishing distinct patterns for carvomenthone-like compounds and menthone-like compounds.

Kallisteine A and B, two new coumarins from the roots of Peucedanum paniculatum L, a species endemic to Corsica.

From the dichloromethane extract of the roots of Peucedanum paniculatum L., two new coumarins, a species endemic to Corsica, have been isolated. Their structures were elucidated, on the basis of spectroscopic studies, particularly 1D and 2D NMR spectroscopy, as 6-(7'-beta-cyclolavandulyl)-7-hydroxycoumarin 1 and a spirodihydrofurano-coumarin 2 (Kallisteine A and B).

Beta-cyclolavandulyl and beta-isocyclolavandulyl esters from Peucedanum paniculatum L., an endemic species to Corsica.

Eight cyclolavandulyl esters (beta-cyclolavandulyl and beta-isocyclolavandulyl acetate, propionate, isobutyrate, isovalerate) were identified in the leaf and root oils of Peucedanum paniculatum L., an endemic species to Corsica, by comparison of their spectroscopic data with those of synthetic material. Their structures were elucidated by spectroscopic methods.

Prevalence rates of respiratory symptoms and diseases in general population samples of North and Central Italy.

Setting: Four cross-sectional general population surveys in Italy: northern rural Po Delta area (1980-1982, n = 3284; 1988-1991, n = 2841), and central urban Pisa area (1985-1988, n = 3865; 1991-1993, n = 2841).

Objective: To analyse changes in prevalence rates of respiratory symptoms and diseases.

Design: Prospective epidemiological studies by standardised interviewer-administered questionnaire.

The Po River Delta Respiratory Epidemiological Survey: an analysis of factors related to level of total serum IgE.

The purpose of the present study was to analyse whether sex, age, skin test reactivity, cigarette smoking and occupational exposure were related to the total serum immunoglobulin (Ig)E concentrations (kU x L[-1]), in a general population sample. We studied 1,905 subjects (915 males, 990 females) of a general population sample (n=2,841, 8-73 yrs) participating in the second cross-sectional respiratory epidemiological survey in the rural Po Delta area (near Venice, North Italy). Distribution of total serum IgE concentrations was skewed, thus a log-transformation was performed to obtain a Gaussian shape.