Publications by authors named "M Vastarella"
Article Synopsis
- This study investigates the link between inflammation markers (NLR, MLR, PLR) and deep myometrial infiltration in patients with endometrial cancer.
- Conducted at AOU Vanvitelli in Naples, Italy, the research involved 161 patients, examining pre-surgery blood counts and relevant histopathological data using statistical analysis software.
- The findings reveal that while both NLR and MLR are associated with deep myometrial infiltration, only NLR remained significant after accounting for other risk factors like grading and histotype.
Objective: This study aimed to evaluate the efficacy of a new biomarker, termed SIR-En, in identifying patients at risk of endometrial carcinoma among those presenting with abnormal uterine bleeding during menopause.
Material And Methods: A retrospective case-control analysis was conducted on 242 women with menopausal abnormal uterine bleeding and endometrial thickness ≥ 4 mm. Peripheral blood samples were collected within 7 days before histological diagnosis.
Article Synopsis
- Ovulatory dysfunction is linked to obesity, with anovulatory women having larger waist sizes and more abdominal fat, highlighting the need to study the relationship between BMI and reproductive traits.
- The research analyzed data from 183 women categorized by weight status (normal, overweight, obese) and assessed various hormonal and reproductive factors during fertility treatments.
- Findings showed that obese women had lower anti-müllerian hormone levels and a less favorable ratio of oocytes retrieved to FSH administered, emphasizing the need to factor in weight status for fertility assessments and treatment strategies.
Women with endometriosis were deemed more prone to COVID-19 infection in some reports. Considering that endometriosis-related aberrant immune response, understanding how COVID-19 vaccination influences its clinical status is crucial. The aim of this meta-analysis was the evaluate the susceptibility to COVID-19 infection and modifications of symptoms following COVID-19 vaccination in women with endometriosis.
View Article and Find Full Text PDFReal-life effectiveness and safety of baricitinib in patients with severe alopecia areata: A 24-week Italian study.
J Eur Acad Dermatol Venereol
September 2024
Background: Alopecia areata is an autoimmune condition characterized by rapid hair loss in the scalp, eyebrows and eyelashes, for which treatments are limited. Baricitinib, an oral inhibitor of Janus kinases 1 and 2, has been recently approved to treat alopecia areata.
Materials And Methods: We conducted a retrospective study involving 23 medical centres across Italy, enrolling patients affected by severe alopecia areata (SALT >50), for more than 6 months.