Publications by authors named "M Varano"
Background: This study aimed to analyze the potential pathogenic connection between metabolic factors, photoreceptor cell rearrangements, retinal microvascular perfusion, and functional parameters through multifocal electroretinography (mfERG) in type 1 diabetes mellitus (DM1).
Methods: This prospective observational cohort study enrolled DM1 patients (40.5 ± 9.
Article Synopsis
- Bardet-Biedl syndrome (BBS) is a rare genetic disorder with symptoms like vision loss, obesity, extra fingers or toes, cognitive issues, and genitourinary defects, caused by mutations in various genes.
- An 18-year-old boy showing symptoms of BBS underwent genetic testing, but initial methods didn't provide a clear diagnosis until whole-genome sequencing revealed two significant genetic changes affecting the BBS9 protein.
- The study emphasizes the importance of whole-genome sequencing for diagnosing rare diseases and highlights the need for functional validation to better understand the impact of genetic variants.
Purpose: Limited data is available on treatment satisfaction with the management of wet age-related macular degeneration (wAMD) among patients in Italy. In this cross-sectional real-world study, treatment satisfaction with anti-vascular endothelial growth factor (anti-VEGFs) was assessed in patients with wAMD in Italy.
Patients And Methods: This was a non-interventional, cross-sectional survey involving patients with wAMD receiving anti-VEGFs.
Background: In a context of reorganization of the activity, of increase of the psychological, emotional and physical constraints of the nursing staff induced by the first wave of the COVID-19 pandemic, an increase of the anxiety disorders could occur.
Objective: This study aims to assess the prevalence of anxiety disorders in healthcare workers (HCWs) by wards and to investigate medical, personal, and occupational factors associated with anxiety disorder.
Methods: In France, in May 2020, a monocentric observational cross-sectional study was proposed to 285 HCWs of the University Hospital of Saint Etienne, working in 3 types of randomly selected care wards.
The high prevalence of Diabetic macular edema (DME) is a real global health problem. Its complex pathophysiology involves different pathways. Over the last decade, the introduction of intravitreal treatments has dramatically changed the management and prognosis of DME.
View Article and Find Full Text PDF