Description of genome sequences of arthropod-associated spirochetes of the genus .

Spirochetal bacteria isolated from arthropods of the genera and are termed BR149, BR151 (), BR193 (), and BR208 (). Genome sizes assembled from Illumina MiSeq and Oxford Nanopore reads varied between 1.67 and 1.

Mlf mediates proteotoxic response via formation of cellular foci for protein folding and degradation in Giardia.

Myeloid leukemia factor 1 (Mlf1) was identified as a proto-oncoprotein that affects hematopoietic differentiation in humans. However, its cellular function remains elusive, spanning roles from cell cycle regulation to modulation of protein aggregate formation and participation in ciliogenesis. Given that structurally conserved homologs of Mlf1 can be found across the eukaryotic tree of life, we decided to characterize its cellular role underlying this phenotypic pleiotropy.

Laser Metal Printing from Nanoparticles Prepared by a Gas Aggregation Source.

This study demonstrates the use of nanoparticles prepared by a gas aggregation source for fabricating structures by combining laser sintering and ablation. At first, the morphology and optical properties of prepared nanoparticle coatings were characterized. Then, the response of coatings to laser irradiation at different powers or exposure times was studied by in situ time-of-flight mass spectrometry, followed by scanning electron microscopy measurements of the resulting structures.

Haptoglobin is dispensable for haemoglobin uptake by .

Haptoglobin is a plasma protein of mammals that plays a crucial role in vascular homeostasis by binding free haemoglobin released from ruptured red blood cells. can exploit this by internalising haptoglobin-haemoglobin complex to acquire host haem. Here, we investigated the impact of haptoglobin deficiency (Hp-/-) on infection and the parasite´s capacity to internalise haemoglobin in a Hp-/- mouse model.