Publications by authors named "M Van Nuffel"
Article Synopsis
- The study examines whether adding the anti-inflammatory drug celecoxib can enhance treatment outcomes for patients with Dupuytren contracture (DC) who are at high risk of recurrence after collagenase therapy.
- A randomized trial with 32 patients showed that celecoxib resulted in significantly better improvements in Total Passive Extension Deficit (TPED) and joint contractures compared to the control group.
- Although celecoxib improved pain and satisfaction scores, the other assessed measures showed no significant differences between the treatment and control groups, suggesting potential benefits of celecoxib for certain outcomes related to DC.
Article Synopsis
- Collagenase clostridium histolyticum (CCH) is a non-surgical treatment for Dupuytren Disease, but recurrence rates are high and predictors of these outcomes are not well understood.
- A study of 74 patients over 5 years showed a 67% recurrence rate after CCH treatment, with no correlation found between the Dupuytren Diathesis Score (DDS) and recurrence.
- However, the presence of knuckle pads was linked to a lower risk of recurrence, and overall patient satisfaction with CCH treatment was reported as high.
In the long term, limited fasciectomy is currently the most reliable treatment for Dupuytren's contracture. The risk for complications is significant, certainly in recurrent disease and in the presence of abundant scar tissue. Meticulous surgical technique is mandatory.
View Article and Find Full Text PDFPhysician-Specific Symptoms of Burnout Compared to a Non-Physicians Group.
Int J Environ Res Public Health
February 2023
Physician burnout is a systemic problem in health care due to its high prevalence and its negative impact on professional functioning and individual well-being. While unique aspects of the physician role contributing to the development burnout have been investigated recently, it is currently unclear whether burnout manifests differently in physicians compared to the non-physician working population. We conducted an individual symptom analysis of burnout symptoms comparing a large sample of physicians with a non-physician group.
View Article and Find Full Text PDFThe treatment of Dupuytren disease (DD) continues to evolve. New insights in risk factors for recurrence and new treatment modalities have changed the management strategies for DD over the past decades. However, several differences may remain between these insights and their clinical application.
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