Introducing a novel "real-time" outbreak alert and notification system to monitor SARS-CoV-2 outbreaks and case fatality in elderly care facilities, the Netherlands, 2020-2022.

Surveillance systems collating individual-level data may limit timely information sharing during rapidly evolving, infectious disease outbreaks. We present a digital outbreak alert and notification system () in which institutional-level data are reported, allowing real-time outbreak monitoring in elderly care facilities (ECF). We describe trends in the number of outbreaks, mean case number per outbreak, and case-fatality rate (deaths/recovered + deaths) of SARS-CoV-2 in ECF notified through in the Rotterdam area (April 2020-March 2022).

The development of metaphorical language comprehension in typical development and in Williams syndrome.

The domain of figurative language comprehension was used to probe the developmental relation between language and cognition in typically developing individuals and individuals with Williams syndrome. Extending the work of Vosniadou and Ortony, the emergence of nonliteral similarity and category knowledge was investigated in 117 typically developing children between 4 and 12 years of age, 19 typically developing adults, 15 children with Williams syndrome between 5 and 12 years of age, and 8 adults with Williams syndrome. Participants were required to complete similarity and categorization statements by selecting one of two words (e.

Exploring the Williams syndrome face-processing debate: the importance of building developmental trajectories.

Background: Face processing in Williams syndrome (WS) has been a topic of heated debate over the past decade. Initial claims about a normally developing ('intact') face-processing module were challenged by data suggesting that individuals with WS used a different balance of cognitive processes from controls, even when their behavioural scores fell within the normal range. Measurement of evoked brain potentials also point to atypical processes.

Early outcome after sirolimus-eluting stent implantation in patients with acute coronary syndromes: insights from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry.

Objectives: This study evaluated the early outcomes of patients with acute coronary syndromes (ACS) treated with sirolimus-eluting stents (SES).

Background: The safety of SES implantation in patients with a high risk for early thrombotic complications is currently unknown.

Methods: Sirolimus-eluting stents have been utilized as the device of choice for all percutaneous procedures in our institution, as part of the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry.

Developmental changes in the effect of inversion: using a picture book to investigate face recognition.

A novel child-oriented procedure was used to examine the face-recognition abilities of children as young as 2 years. A recognition task was embedded in a picture book containing a story about two boys and a witch. The story and the task were designed to be entertaining for children of a wide age range.