The fruit fly is a model organism to study several aspects of metazoan biology. Most of the work has been conducted in adult fruit flies, including laboratory and field-derived specimens, but larvae recently became a valuable model to better understand animal physiology, development, or host-microbe interactions. While adult flies can be easily assigned to a given species based on morphological characteristics, such visual identification is more intricate at the larval stage.
View Article and Find Full Text PDFObjectives: The aim of this study was to evaluate pristinamycin in the treatment of MSSA bone and joint infection (BJI).
Patients And Methods: A retrospective, single-centre cohort study (2001-11) investigated outcome in adults receiving pristinamycin for MSSA BJI and pristinamycin-related adverse events (AEs).
Results: One hundred and two MSSA BJIs were assessed in 98 patients [chronic infection, 33.
Chemo-mechanotransduction, the way by which mechanical forces are transformed into chemical signals, plays a fundamental role in many biological processes. The first step of mechanotransduction often relies on exposure, under stretching, of cryptic sites buried in adhesion proteins. Likewise, here we report the first example of synthetic surfaces allowing for specific and fully reversible adhesion of proteins or cells promoted by mechanical action.
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