Publications by authors named "M VOORTMAN"
Background: The rotational position of the aortic root (AoR) is of substantial clinical interest as it has been associated with severe aortic complications, such as aortic dissections. We described a cardiac magnetic resonance (CMR)-based method for measuring AoR rotation and evaluated the reliability of measurements.
Methods: CMR was used for measuring AoR rotation in 50 consecutive healthy subjects.
Sarcoidosis is an immune-mediated multisystem granulomatous disorder. Neurosarcoidosis (NS) accounts for 5% to 35% of cases. The diagnostic evaluation of NS can be a clinical challenge.
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- Intrathecal IgM production in multiple sclerosis (MS) is correlated with a more severe disease progression.
- Researchers analyzed cerebrospinal fluid (CSF) from MS patients and controls to identify autoreactive IgM antibodies, discovering that about 10% of MS patients had unique IgM binding profiles.
- One specific IgM antibody was linked to increased immune cell activity in the brain and was found to target a protein called SCARA5, suggesting that IgM may play a role in promoting inflammation in MS.
Aims: To characterize the pharmacokinetic and pharmacodynamic properties of once-weekly insulin icodec in type 2 diabetes (T2D).
Materials And Methods: In an open-label trial, 46 individuals with T2D (18-75 years; body mass index 18.0-38.
Background: Connective tissue diseases-associated interstitial lung disease (CTD-ILD) is a heterogeneous condition that impairs quality of life and is associated with premature death. Progressive pulmonary fibrosis (PPF) has been identified as an important risk factor for poor prognosis. However, different criteria for PPF are used in clinical studies, which may complicate comparison between trials and translation of study findings into clinical practice.
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