Publications by authors named "M VANDEKERCKHOVE"

Background: Fragmented rapid eye movement (REM) sleep disrupts the overnight resolution of emotional distress, a process crucial for emotion regulation. Emotion dysregulation, which is common across psychiatric disorders, is often associated with sleep disturbances. This systematic review explores how REM sleep and nightmares affect emotion processing and regulation in individuals with psychiatric disorders where emotion dysregulation is a key concern, suggesting novel sleep-related treatment pathways.

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  • The study aims to understand how the vestibulocochlear system is affected in patients with Susac syndrome (SuS), which is a rare condition that impacts the brain, eyes, and inner ear.
  • A review of 21 patient files shows that most experienced various audiovestibular symptoms, including vertigo and sensorineural hearing loss, with specific audiological and vestibular testing revealing common patterns of dysfunction.
  • The findings suggest that early treatment with immunosuppressive therapy can help prevent severe audiovestibular problems, indicating the need for more research to understand the underlying causes and improve patient outcomes.
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  • Whole-genome sequencing (WGS) is transforming clinical bacteriology but traditional bacterial typing methods have limitations, prompting the search for more accurate alternatives.
  • A study optimized a nanopore sequencing protocol to evaluate two alternative typing methods alongside antibiotic resistance profiling using clinical bacterial isolates.
  • Results showed that the new methods (ANI and DDH) correlated well with standard multi-locus sequence typing (MLST) and provided better strain resolution, while WGS-based antibiotic resistance predictions were accurate for certain antibiotics, but less reliable for others.
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Background Dislocation is one of the most prominent and challenging complications following the revision of total hip arthroplasty (THA). Dual-mobility cups are an option to address this problem. There is, however, little data on the outcomes of modern modular dual-mobility (MDM) cups in the revision of THA.

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Accurate DNA quantification is key for downstream application including library preparations for whole genome sequencing (WGS) and the quantification of standards for quantitative PCR. Two commonly used technologies for nucleic acid quantification are based on spectrometry, such as NanoDrop, and fluorometry, such as Qubit. The DS-11+ Series spectrophotometer/fluorometer (DeNovix) is a UV spectrophotometry-based instrument and is a relatively new spectrophotometric method but has not yet been compared to established platforms.

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