Laser irradiation as a potential pathogenetic method for immunocorrection in rheumatoid arthritis.

We investigated the immunocorrective and clinical effect in 75 rheumatoid patients treated with intravenous laser blood irradiation. A relation between the positive immunotropic (as well as therapeutic) effect and the pre-existent immune status of each patient was revealed. A well-defined effect was found in patients with a low level of CIC and a normal count of functional-competent T-cells.

[Analysis of immune disorders in patients with rheumatoid arthritis and heart involvement].

Examinations of 121 patients with rheumatoid arthritis (RA) included immunological testing for antinuclear antibodies (ANA), lymphocyte blastogenesis test, and leukocyte migration inhibition test and functional cardiological examinations (ECG and EchoCG). RA patients with positive ANA test (n = 43) more often developed immune disorders: the titer of rheumatoid factor was higher and antibodies to type I collagen were more often detected; this was paralleled by decreased cellular immunity and macrophage formation in spontaneous lymphocyte blastogenesis test. The same group more often had ECG and EchoCG deviations.

[Functional disturbances of the immune system in rheumatic diseases and their dynamics in the context of pathogenetic therapy].

Immunological investigations in patients with rheumatic diseases (rheumatoid arthritis, Reiter's disease, infectious endocarditis, rheumatic heart disease) evidence that the time of onset of different immunologic pathogenetic mechanisms was the same. Immunological rehabilitation was achieved by different therapeutic methods: drugs, plasmapheresis, hemosorption, electrophoresis, ultrasound. In experiments it was beta-1-trophoblastic glycoprotein.