Publications by authors named "M V de Abreu"
Tyramine, β-phenylethylamine, octopamine and other trace amines are endogenous substances recently recognized as important novel neurotransmitters in the brain. Trace amines act via multiple selective trace amine-associated receptors (TAARs) of the G protein-coupled receptor family. TAARs are expressed in various brain regions and modulate neurotransmission, neuronal excitability, adult neurogenesis, cognition, mood, locomotor activity and olfaction.
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- Antimicrobial resistance (AMR) is a significant global public health issue, prompting this study to examine antibacterial usage and the prevalence of multidrug-resistant organisms (MDRO) in a Brazilian hospital, particularly focusing on the ESKAPE group pathogens.
- The study employed a time series approach, analyzing data from January 2015 to December 2021, revealing increased consumption of specific antibiotics like daptomycin and linezolid, and a noteworthy rise in the incidence of certain MDROs, especially Staphylococcus spp and Enterococcus spp.
- Findings suggest that the COVID-19 pandemic may have worsened the trends of rising AMR, highlighting the need for ongoing surveillance to understand these epidemiological changes better.
Quality of Oral Anticoagulation Control with Warfarin According to Sex: A Cross-Sectional Study.
Int J Environ Res Public Health
January 2025
Evidence indicates a difference between men and women in oral anticoagulation control, but the results were discrepant. This study investigated the association of sex with oral anticoagulation control in patients on warfarin assisted by anticoagulation clinics (ACs) in Brazil. The cross-sectional study included patients on warfarin recruited at three public ACs in southeast Brazil (2014-2015).
View Article and Find Full Text PDFWe investigated the role of uric acid in the pathogenesis of severe malaria (SM) in two independent cohorts of children with SM. Hyperuricemia (blood uric acid ≥ 7 mg dl) was present in 25% of children with SM and was associated with increased in-hospital mortality and postdischarge mortality in both cohorts. Increased blood uric acid levels were also associated with worse scores in overall cognition in children with SM < 5 years old in both cohorts.
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