[Decolonization of autologous blood with cefuroxime during hardware reinfusion in neurosurgical patients].

Unlabelled: Autologous blood obtained during hardware reinfusion can be bacterially contaminated with skin microflora in most cases (up to 90%) regardless of the area of surgical intervention. Increased volume of washing solution for red blood cell management, white blood cell filtration and X-ray irradiation do not always provide complete decontamination.

Objective: To analyze the effectiveness of adding cefuroxime to extracorporeal circuit during hardware blood reinfusion.

[Bacterial contamination of autologous blood in reinfusion in neurosurgery: a phenomenon or a problem?].

Unlabelled: There is a problem of bacterial contamination of autologous blood despite long-term experience of intraoperative blood salvage and reinfusion.

Objective: To analyze safety of blood reinfusion with white blood cell filtration and X-ray irradiation for blood decontamination in neurosurgery.

Material And Methods: The study included 57 patients with various neurosurgical diseases.

[Diagnosis and antibiotic therapy of nosocomial pneumonia in adults: from recommendations to real practice. A review].

Nosocomial pneumonia is a healthcare-associated infection with significant consequences for the patient and the healthcare system. The efficacy of treatment significantly depends on the timeliness and adequacy of the antibiotic therapy regimen. The growth of resistance of gram-negative pathogens of nosocomial pneumonia to antimicrobial agents increases the risk of prescribing inadequate empirical therapy, which worsens the results of patient treatment.

Different Trajectories of Apathy and Depression Among Subjective Cognitive Impairment Individuals with or without Conversion to Dementia: Results from the Memento Cohort in France.

Background: Apathy and depression are two early behavioral symptoms in Alzheimer's disease (AD) and related disorders that often occur prior to the onset of cognitive decline and memory disturbances. Both have been associated with an increased risk of conversion to dementia, with a distinct neuropathology.

Objective: The assessment of the trajectories of apathy and depression and their independent impact on dementia conversion.

Infectious complications in acute period after traumatic brain injury.

Unlabelled: Patients with traumatic brain injury (TBI) are at high risk of infection.

Objective: To delineate infections in acute period of TBI, association between intracranial lesion type and risk of infection, as well as to estimate treatment outcomes in these patients depending on infection.

Material And Methods: This study included 104 patients with TBI (80 men and 24 women) aged 33.