Effect of chalone system on proliferation of Ehrlich ascitic tumor cells under conditions of modified photoregimen.

We studied the influence of different photoregimens (light/darkness alternation and constant darkness) on the effect of saline and chalone regulation of cell proliferation in Ehrlich ascitic tumor was studied. Saline slightly inhibited proliferation of tumor cells. Chalone-containing preparations from animals exposed to light/darkness alternation and to constant darkness were characterized by different effects on cell proliferation in this tumor.

Carnosine as a potential anti-senescence drug.

The naturally occurring dipeptide carnosine (beta-alanyl-L-histidine) has been found to exert an anti-senescence effect when used as a dietary supplement. Carnosine clearly improved the external appearance of experimental animals and provided beneficial physiological effects, thus maintaining the animals in better condition than control animals receiving no carnosine or a mixture of beta-alanine and L-histidine.