Profile of care for children and adolescents at a gender-affirming outpatient clinic within the Brazilian National Health System in São Paulo, Brazil, between 2009 and 2020.

Objective: To describe the profile of transgender children and adolescents receiving care at a gender affirming outpatient clinic within the Brazilian National Health System (Sistema Único de Saúde - SUS) in São Paulo.

Methods: This was a descriptive study involving 555 participants, who received care between 2009 and 2020, in tertiary care services of the SUS. Data were analyzed using Pearson's chi-square test and standard deviation, considering gender, age, and origin.

Differences in Clinical Profiles and Biologic Treatment Approaches for Autoimmune Rheumatic Diseases Across Regions in Mexico: An Analysis of the BIOBADAMEX Cohort.

Objective: Being Mexico a very diverse developing country, the access to health care varies among geographical regions. We aimed to assess the differences in clinical features and treatment prescription in 3 regions of Mexico using data from the Mexican Adverse Events Registry (BIOBADAMEX).

Methods: We included all BIOBADAMEX patients from 2016 to 2023, compared the prescription patterns, the sociodemographic, clinical, and treatment characteristics between the northern (NR), central (CR), and southern regions (SR), and addressed the treatment survival by calculating hazards ratios (HRs).

The role of the proteosurfaceome and exoproteome in bacterial coaggregation.

Bacterial coaggregation is a critical process in multispecies biofilm formation, driven by specific molecular interactions that facilitate the adhesion and aggregation of bacterial cells. These interactions are essential for the development and persistence of complex microbial communities. This review provides a comprehensive analysis of the roles of the proteosurfaceome and exoproteome in bacterial coaggregation.

Analysing macroscopic traffic rhythms and city size in affluent cities: insights from a global panel data of 25 cities.

The world is undergoing a rapid process of urbanization. Currently, it is estimated that over 55% of the global population resides in urban areas, a figure projected to reach nearly 70% by 2050. This trend is accompanied by a spatial reorganization of human activities on a global scale, bringing about significant changes in mobility patterns and urban traffic management capabilities.