Publications by authors named "M V Rybakova"

Objective: To study the clinical and morphological manifestations of lung sequestration.

Material And Methods: Surgical material (lung tissue) of 18 patients (2017-2021) and 8 archival observations (1972-1994) of confirmed lung sequestration were examined. Histological staining (hematoxylin and eosin, Schiff reagent, Ziehl-Neelsen, picrofuchsin according to Van Gieson) and immunohistochemical reactions with antibodies to SMA, TTF1, CK5/6 (DAKO) were performed.

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Article Synopsis
  • The literature review discusses how COVID-19 can lead to pulmonary fibrosis by exploring the underlying mechanisms associated with the SARS-COV2 virus infection.
  • Key factors contributing to lung remodeling after COVID-19 include direct damage from the virus, inflammatory responses due to cytokine imbalance, and issues with blood vessel function.
  • The review highlights that the abnormal activation of the renin-angiotensin-aldosterone system, combined with other contributing factors, creates an imbalance that promotes fibrosis in the lungs.
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IgG4-related disease is an immune-mediated disorder with tumor-like multiorgan involvement, elevated serum IgG4 level and specific histopathological appearance (lymphoplasmacytic infiltrate rich in IgG4+ plasma cells and storiform fibrosis). The article presents rare clinical and morphological observations of IgG4-related mastopathy in women with suspected tumor process. A strategy for the treatment of IgG4-related disease should be based on the results of pre-surgery histopathological examination, which may help to avoid unreasonable surgical intervention and choose glucocorticoids or rituximab as the first-line treatment.

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The paper presents basic morphological criteria of the diagnosis of sudden cardiac death related to different diseases in young people. Attention is drawn to cardiomyopathies, channelopathies, connective tissue dysplasias, Marfan syndrome with cystic medial necrosis, sudden arrhythmic death. Initiating events in sudden cardiac death are discussed.

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Unlabelled: The cardiovascular system is a common target of systemic amyloidosis (SA); amyloid light chain (AL) cardiac amyloidosis (AL-CA), the wild-type transthyretin (ATTRwt-CA), and mutant-type transthyretin (ATTRmt-CA) are the most studied types of SA. The literature describes only single cases of two types of SA in the same patient.

Objective: To identify and determine the clinical and morphological characteristics of combined types of SA in patients with biventricular chronic heart failure (CHF).

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