[Influenza virus sensitivity to interferon and its inducer].

The results of the study on influenza virus sensitivity to interferon of two kinds (human and chicken) and its inducer, poly(G) . poly(C) are presented. Differences in this characteristic among human and animal influenza viruses were demonstrated.

[Antigenic recombinants of human influenza viruses with viruses isolated from wild birds].

Antigenic recombinants obtained by crossing of different human and animal influenza viruses were studied for some genetic markers and specific proteins in the resulting recombinants were analyses. In a number of cases the origin of inner virion proteins (NP and M) from one or the other parent and nonstructural NS proteins was established.

[Production of recombinants antigenically identical to influenza virus strains circulating in nature].

Recombination of a human influenza virus with an avian influenza virus produced a H2Nav2 recombinant with the antigenic properties analogous to those of avian influenza virus (H2Nav2) isolated from wild ducks in the Far East, USSR. Recombination of two avian influenza viruses yielded a recombinant H2N2, an antigenic analogues of influenza A/Singapore/1/57 (H2N2) virus which had started an epidemic of influenza in 1957.