Apical Surgery and Resurgery After Recurrent Failure in Traumatised Immature Teeth: Reflections on Management Based on Two Case Reports.

This study reports two cases of traumatised non-vital immature teeth (IT). Both underwent surgical and nonsurgical treatments after healing failure. In the first case, both maxillary central incisors underwent revascularization as the first treatment option.

Can a brief guided nature walk reduce distress and improve resilience, mindful attention, and sleep quality? Evidence from a pilot study with two-week follow-up.

Despite trends of deteriorating mental health globally, help-seeking remains suboptimal. Identifying less stigmatising, low-cost, and scalable approaches to mental health care is critical. We investigated the acceptability and psychological benefits of a 30-minute guided nature walk programme in an accessible country park in Hong Kong among 100 community members.

Sudden Fall Detection of Human Body Using Transformer Model.

In human activity recognition, accurate and timely fall detection is essential in healthcare, particularly for monitoring the elderly, where quick responses can prevent severe consequences. This study presents a new fall detection model built on a transformer architecture, which focuses on the movement speeds of key body points tracked using the MediaPipe library. By continuously monitoring these key points in video data, the model calculates real-time speed changes that signal potential falls.

Reinterpretation of Conflicting ClinVar Missense Variants Using VarSome and CanVIG-UK Gene-Specific Guidance.

Background: The accurate interpretation of the /2 variant is critical for diagnosing and treating hereditary breast and ovarian cancers. ClinVar is a widely used public database for genetic variants. Conflicting classifications of pathogenicity can occur when different submitters categorize the same genetic variant inconsistently as pathogenic (PV), likely pathogenic (LPV), likely benign (LBV), benign (BV), or a variant of uncertain significance (VUS).

The pathogenesis of gout.

Gout is the most common inflammatory arthritis in adults, associated with hyperuricemia and the chronic deposition of monosodium urate (MSU) crystals. Hyperuricemia results from increased production of uric acid and decreased excretion by the kidneys and intestines. Urate excretion is regulated by a group of urate transporters, and decreased renal or intestinal excretion is the primary mechanism of hyperuricemia in most people.