Performance of transesophageal echocardiography probe at temperature monitoring during simulated hypothermia and rewarming.

Objective: To determine whether a transesophageal echocardiography (TEE) probe can accurately measure temperature and be used to monitor temperature changes over time without overheating in an experimental model of hypothermia and rewarming.

Methods: A 6L water bath was heated with a sous vide immersion circulator to 24C, 28C, 32C and 36C to simulate severe hypothermia, moderate hypothermia, mild hypothermia, and normothermia. A TEE probe, esophageal temperature probe, and bladder temperature probe were used to measure temperature.

Perturbation therapies for neurodegenerative disorders: How attractors of excitable networks can help.

We investigate the influence of the network topology on the asymptotic dynamical patterns, attractors, in a general model of excitable dynamics on signed directed graphs. In this framework, network topology manifests itself as an interplay of positive and negative feedback loops. A small change in a feedback loop, by addition or removal of edges in the graph, can drastically change the dynamical patterns in the network, characterized by the appearance and disappearance of attractors from the attractor space of the network.

The Formation of γ-Valerolactone from Renewable Levulinic Acid over Ni-Cu Fly Ash Zeolite Catalysts.

Zeolites with different structures (P1, sodalite, and X) were synthesized from coal fly ash by applying ultrasonically assisted hydrothermal and fusion-hydrothermal synthesis. Bimetallic catalysts, containing 5 wt.% Ni and 2.

Osimertinib-Induced Toxic Epidermal Necrolysis - A Case Report.

Purpose: To investigate the rare side effects of Osimertinib in a case of toxic epidermal necrosis.

Case Presentation: We report on a case of a 44-year old woman with lung adenocarcinoma harboring an EGFR-sensitizing mutation who was treated with Osimertinib as the second-line treatment. Ten days after Osimertinib initiation, a diffuse erythematous rash rapidly spread over the patient's trunk along with vesicles and purpuric macules; furthermore, she developed erythema and exfoliation on the face and trunk and severe mucositis.

Ruminant microbiome data are skewed and unFAIR, undermining their usefulness for sustainable production improvement.

The ruminant microbiome plays a key role in the health, feed utilization and environmental impact of ruminant production systems. Microbiome research provides insights to reduce the environmental footprint and improve meat and milk production from ruminants. However, the microbiome composition depends on the ruminant species, habitat and diet, highlighting the importance of having a good representation of ruminant microbiomes in their local environment to translate research findings into beneficial approaches.