[In-vitro degradation of the chitosan membranes under various syntheses conditions].

The hydrolytic degradation of polymer films, which were obtained by application of 2% and 3% chitosan solutions in 1% acetic acid on a base sheet has been investigated. As the solvent was removed, these firms were either treated with 0.5% NaOH for 3 min or with phosphate buffer (рН 8) for 10 min.

Characterization and in vivo evaluation of chitosan-hydroxyapatite bone scaffolds made by one step coprecipitation method.

Chitosan/hydroxyapatite scaffolds could be used for bone regeneration in case the application of auto- or allografts is impossible. The objective of the present work was to characterize and study in vivo biodegradation of simple chitosan/hydroxyapatite scaffolds. For this purpose, a series of chitosan/hydroxyapatite composites has been synthesized in aqueous medium from chitosan solution and soluble precursor salts by a one step coprecipitation method.