[Therapy of psychotic schizophrenia spectrum disorders in adolescents].

Objective: To assess the clinical efficacy, tolerability and safety of prolonged treatment with paliperidone in adolescents with the exacerbation of psychotic schizophrenia spectrum disorders.

Material And Methods: Thirty-six adolescents at the age from 14 to 18 years with ICD-10 diagnosis F20-21, F25 were examined by clinical/psychopathological method (PANSS and CGI scale). The duration of the disease was from 1 to 3 years.