Publications by authors named "M V Pikul"

Unlabelled: The current study aimed to evaluate short- and long-term complication rates and functional outcomes in a substantial cohort of patients undergoing ileal ureter interposition at two high-volume medical centres.

Materials And Methods: A retrospective single-arm analysis was conducted on patients who underwent ureter reconstruction using ileum between 2003 and 2022 at the University Clinic of Cologne and the National Cancer Institute of Ukraine. Data on aetiology, surgical techniques, pre- and postoperative kidney function changes, readmission rates and complication management were collected.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to identify key factors influencing the choice of surgical treatment for patients with localized Renal-Cell Carcinoma (RCC) using clinical and nephrometry data.
  • It involved a retrospective analysis of patients who underwent surgery for localized RCC between 2010 and 2017 and used multivariate predictive modeling to assess risks associated with surgical options.
  • Results indicated that the risks for partial nephrectomy (PN) were linked to remaining functioning kidney tissue volumes for polar and lateral tumors, while tumor size was the main factor for medial tumors, with the predictive model showing high sensitivity (95.2%) and specificity (95.4%).
View Article and Find Full Text PDF

Aim: This study aims to assess the effectiveness of urothelial cancer treatment in Ukraine, utilizing population-based data from the National Cancer Registry. The primary goal is to evaluate trends and approaches to therapy, with a focus on overall survival rates in patients with urothelial tumors.

Materials And Methods: A retrospective cross-sectional analysis was conducted based on the National Cancer Registry, involving 12 698 patients (2008-2020) with urothelial tumors of the upper urinary tract (UTUC) and bladder cancer (BC) who underwent surgical treatment.

View Article and Find Full Text PDF

Purpose: This study aimed to estimate the difference between peripheral and central small renal lesions in terms of their oncologic potential.

Methods: Cross-sectional retrospective analysis of patients with small renal masses (T1a) who underwent surgical treatment between January 2008 and July 2019 at the affiliated hospital. Only patients with ccRCC pathology were included.

View Article and Find Full Text PDF

Introduction: The study aimed to evaluate the objective response level to neoadjuvant platinum-based chemotherapy and tumour complexity reduction in patients with invasive upper tract urothelial cancer (UTUC), and to estimate the functional and oncological outcomes of the combined organ-sparing approach compared to radical nephroureterectomy.

Material And Methods: This prospective, non-randomised cohort study was conducted by the National Cancer Institute of Ukraine. Patients with invasive UTUC were enrolled between October 2016 and January 2021.

View Article and Find Full Text PDF