Publications by authors named "M V Lekishvili"

Accuracy of diagnosis defines the quality of treatment in patients with traumatic damage to eyelet walls. In this area, complex functional and anatomical breaches are typical and require full characterization of pathological changes in bone and soft tissue structures. A new plastic material with a high degree level of demineralization called "Perfoost" can be used to treat defects in the bones of the face of children and adults.

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The objective of the present study was to enhance the effectiveness of the surgical treatment of chronic suppurative otitis media (CSOM) by means of the application of the Perfoost demineralized bone alloimplant for the plastic reconstruction of the posterior wall of the external auditory canal. This aim was attained by the elucidation of morphological features the Perfoost alloimpalnt at the site of surgical intervention one year after the operation. The study included 12 patients presenting with CSOM (epi- and epimesotympanitis) who had underwent "closed-type" sanation surgery of the middle ear.

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Drug induced hypersensitivity syndrome (DIHS) is a rare but potentially life-threatening adverse drug reaction particularly associated with anticonvulsant drugs. We describe the case of a patient who suffered from DIHS caused by anticonvulsant. Our experience suggests glucocorticoids (GC) may be of benefit to children with severe DIHS.

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New partially demineralized Perfoost allografts were used for the treatment of nasal septum defects in 16 patients admitted to the Research and Clinical Otorhinolarygological Centre, Federal Healthcare and Social Development Agency, between January 2007 and November 2008. The length of the follow-up period varied from 6 months to 1 year 10 months. The plastic material manufactured in the form of plates of different size was obtained from the bank of autografts based at the Central Institute of Traumatology and Orthopedics.

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Positive properties and perspectivity of demineralized osseous allogenic implants were pointed to. Experimental model of primary osseous plasty of mandible defects was described. The comparison of character and pace of reparative osteogenesis in experimental bone defects with Perfoost use and without transplantation was done.

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