Effect of Bacteria from the Genus on Oxidative Stress Levels in Wheat L. in the Presence of Copper, Nickel, and Lead.

Heavy metals (HMs) exert a negative impact on physiological processes in plants, which can adversely affect the productivity of agricultural crops. In this experiment, we assessed the potential to mitigate the toxic effects of HMs on soft wheat through the use of rhizospheric microorganisms from the genus . In the initial phase of the experiment, we identified the most resistant strains to Cu (from 1.

Cu-Methylsilsesquioxane Cage Decorated with Cu(dppe) Moieties for Mild Oxidative Functionalization of Alkanes.

We report a high nuclear (Cu) complex synthesized via the self-assembly of copper-methylsilsesquioxane induced by the complexation with 1,2-bis(diphenylphosphino)ethane (dppe). The structure includes two cationic Cu(dppe) moieties and an anionic silsesquioxane cage of an unprecedented Cu structural type. The Cu cage fragment exhibits a unique () combination of Si-cyclic/Si-acyclic silsesquioxane ligands and () encapsulation of two different chloride and carbonate species.

Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain.

Proteolysis Targeting Chimeras (PROTACs) are bifunctional molecules that simultaneously bind an E3 ligase and a protein of interest, inducing degradation of the latter via the ubiquitin-proteasome system. Here we present the development of degraders targeting CREB-binding protein (CBP) and E1A-associated protein (EP300)-two homologous multidomain enzymes crucial for enhancer-mediated transcription. Our PROTAC campaign focused on CPI-1612, a reported inhibitor of the histone acetyltransferase (HAT) domain of these two proteins.

Chiral arylsulfinylamides as reagents for visible light-mediated asymmetric alkene aminoarylations.

Two- or one-electron-mediated difunctionalizations of internal alkenes represent straightforward approaches to assemble molecular complexity by the simultaneous formation of two contiguous Csp stereocentres. Although racemic versions have been extensively explored, asymmetric variants, especially those involving open-shell C-centred radical species, are much more limited both in number and scope. Here we describe enantioenriched arylsulfinylamides as all-in-one reagents for the efficient asymmetric, intermolecular aminoarylation of alkenes.

Coordination Polymers from an Amino-Functionalized Terphenyl-Tetracarboxylate Linker: Structural Multiplicity and Catalytic Properties.

An amino-functionalized terphenyl-tetracarboxylic acid, 2'-amino-[1,1':4',1″-terphenyl]-3,3″,5,5″-tetracarboxylic acid (Htpta), was used as an adaptable linker to synthesize, under hydrothermal conditions, eight coordination polymers (CPs). The obtained products were formulated as [Co(μ-Htpta)] (), [Co(μ-Htpta)(2,2'-bipy)] (), [M(μ-Htpta)(2,2'-bipy)] (M = Mn (), Cd ()), [Ni(μ-tpta)(phen)(HO)] (), [Zn(μ-tpta)(phen)] (), {[Zn(μ-tpta)(μ-4,4'-bipy)]·HO} (), and [Zn(μ-tpta)(μ-Hbiim)(HO)] (), wherein 2,2'-bipyridine (2,2'-bipy), 4,4'-bipyridine (4,4'-bipy), 1,10-phenanthroline (phen), or 2,2'-biimidazole (Hbiim) are present as additional stabilizing ligands. The structural types of - vary from one-dimensional (1D) (, ) and two-dimensional (2D) (, , ) CPs to three-dimensional (3D) metal-organic frameworks (MOFs) (, , and ) with a diversity of topologies.