[Effectiveness of radioprotective action of plaferon LB].

The aim of the study was the investigation of effectiveness of radioprotective action of plaferon LB on rat's ovary during gamma-irradiation. It was established that during irradiation in the rats ovary the mechanisms of follicle genesis ovulation and luteinization are disordered. It was revealed hyperplasia of hormone produced structures by way of thekomatosis.

[Plaferon LB in prevention of radiation-induced changes in lipid metabolism indices and erythrocyte deformability rate].

Oxidative damage of biological membranes plays critical role in the process of radiation-induced damages in tissues and cells. It involves reactive oxygen species generated under ionizing radiation. Development of radiation-induced oxidative stress facilitates the intensification of lipid peroxidation and fatty acid reorganization, which, in its turn, results in decreased lipid matrix fluidity, changes in biophysical properties of membranes, increased rigidity of membrane lipid-protein surface.