3D-MedTranCSGAN: 3D Medical Image Transformation using CSGAN.

Computer vision techniques are a rapidly growing area of transforming medical images for various specific medical applications. In an end-to-end application, this paper proposes a 3D Medical Image Transformation Using a CSGAN model named a 3D-MedTranCSGAN. The 3D-MedTranCSGAN model is an integration of non-adversarial loss components and the Cyclic Synthesized Generative Adversarial Networks.

A Rare Case of Haemoperitoneum in Pregnancy.

Haemoperitoneum in pregnancy is a rare, but potentially fatal condition. Primary hepatocellular carcinoma (HCC) in pregnancy is also very uncommon. Primary hepatocellular carcinoma occuring in a pregnant lady and presenting with massive haemoperitoneum is, to the best of our knowledge, the first case to be reported in world literature.

HPV16 E2 enhances the expression of NF-κB and STAT3 target genes and potentiates NF-κB activation by inflammatory mediators.

HPV-transformed cells exhibit activation of NF-κB and STAT3 (mediators of inflammation), but very little is known about their regulation under inflammatory conditions before HPV integration. This study reports that cervical tissues with stromal inflammation and intact HPV16 E2 gene show increased expression of target genes of NF-κB and/or STAT3 which can regulate cell survival (cyclin D1, c-Myc, survivin and Bcl2) and inflammatory responses (TNF-α, IL-1β, IL-6, IL-8 and CCR2). Increased expression of RelA, p-IκBα, STAT3, p-STAT3 (Ser727), Pin1 (peptidyl-prolyl cis/trans isomerase) and MCM2 in the squamous epithelia of cervices with stromal inflammation supports early activation of NF-κB-STAT3.