Self-Assembly of a Dipeptide with a Reduced Amount of Copper into Antifungal and Antibacterial Particles.

With the growing concern over the environmental impact and health risks associated with conventional pesticides, there is a great need for developing safer and more sustainable alternatives. This study demonstrates the self-assembly of antimicrobial and antifungal spherical particles by a dipeptide utilizing a reduced amount of copper salt compared to the commonly employed formulation. The particles can be sprayed on a surface and form an antimicrobial coating.

Fabrication of antimicrobial polymeric films by compression molding of peptide assemblies and polyethylene.

This paper presents compression molding of peptide assemblies with low-density polyethylene (LDPE) for the robust production of antimicrobial polymeric films. These films show a significant reduction of colony-forming units and plaque-forming units. Moreover, they significantly inhibited the growth of three different fungi.

Effect of the membrane exclusion mechanism on phosphate scaling during synthetic effluent desalination.

Calcium phosphate scaling is one of the main limitations in effluent desalination using membranes. This may be overcome by tailoring membranes with lower rejection of the scalant ions. In this study, we systematically examined the use of negatively and positively charged membranes, rejecting ions mainly based on Donnan exclusion, as a low-scaling alternative to dielectric-exclusion-dominated polyamide NF membranes for effluent desalination.

Phosphorylation of yeast transcription factors correlates with the evolution of novel sequence and function.

Gene duplication is a significant source of novel genes and the dynamics of gene duplicate retention vs loss are poorly understood, particularly in terms of the functional and regulatory specialization of their gene products. We compiled a comprehensive data set of S. cerevisiae phosphosites to study the role of phosphorylation in yeast paralog divergence.

On the relation between promoter divergence and gene expression evolution.

Recent studies have characterized significant differences in the cis-regulatory sequences of related organisms, but the impact of these differences on gene expression remains largely unexplored. Here, we show that most previously identified differences in transcription factor (TF)-binding sequences of yeasts and mammals have no detectable effect on gene expression, suggesting that compensatory mechanisms allow promoters to rapidly evolve while maintaining a stabilized expression pattern. To examine the impact of changes in cis-regulatory elements in a more controlled setting, we compared the genes induced during mating of three yeast species.