Publications by authors named "M V Holt"
Purpose: Remote symptom monitoring of patients with cancer has previously shown potential for improving clinical outcomes. This study aimed to evaluate the effects of remote symptom monitoring in patients with lung cancer after palliative induction treatment.
Methods: In a Danish multicenter randomized controlled trial, patients were randomly assigned 1:1 to remote symptom monitoring (intervention arm) added to standard of care versus standard of care (control arm).
Stress-induced behaviours are driven by complex neural circuits and some neuronal populations concurrently modulate diverse behavioural and physiological responses to stress. Glucagon-like peptide-1 (GLP-1)-producing preproglucagon (PPG) neurons within the lower brainstem caudal nucleus of the solitary tract (cNTS) are particularly sensitive to stressful stimuli and are implicated in multiple physiological and behavioural responses to interoceptive and psychogenic threats. However, the afferent inputs driving stress-induced activation of PPG neurons are largely unknown, and the role of PPG neurons in anxiety-like behaviour is controversial.
View Article and Find Full Text PDFIntroduction: HIV pre-exposure prophylaxis (PrEP) has been publicly available since 2018 in Australia as a daily regimen. In 2019, clinical guidelines were updated to support guidance on event-driven PrEP (ED-PrEP) use. We assessed trends in the PrEP dosing regimen by comparing daily PrEP use to ED-PrEP among cisgender gay, bisexual and other men who have sex with men (GBMSM).
View Article and Find Full Text PDFArticle Synopsis
- Continuous active sonar produces lower sound pressure levels compared to traditional pulsed active sonar but can cause higher auditory masking due to its constant operation.
- The study evaluates how different noise types, including continuous active sonar, affect signal detection in killer whales using both a pure tone and a whale call.
- Results show that while other noise types allowed for some frequency detection, continuous active sonar significantly overlaps with killer whale calls, making it a strong auditory masker.*
Purpose: Transgender and gender diverse youth (TGDY) can be a challenging population to reach because of limitations related to parental/guardian consent and concerns about privacy. This pilot study's purpose was to assess the feasibility of recruiting a US nation-wide longitudinal sample of TGDY through social media, and to compare participants who completed the Wave 1 survey only to TGDY who completed both Wave 1 and Wave 2 surveys.
Methods: Adolescents (aged 14-17 years) who identified as TGDY were recruited through social media and invited to complete two online surveys across a 3-month period.