Electron microscopic characterization of gels formed by blood cells of leukemia patients at hypertonicity.

At hypertonicity some blood cells of patients suffering chronic leukemia can form gel like layers around themselves. These gels, which are sensitive to hyaluronidase, but not to trypsin are investigated by electron microscopy. The study revealed that the gels comprise a network of nanoparticles, which have diameters between 50 and 150 nm, are regularly ordered and linked to each other.

[Permeabilization of tumor cells induced by pulsed electric fields in vitro].

The permeabilization of tumor cells in vitro under the action of pulsed electric fields with a duration of 6 mks in the range of amplitudes 1-7 kV/cm was studied. In the mode of excitation in the ambience of localized plasma discharge in a chamber of special design, an enhanced damage to cells in suspension was observed. It is assumed that the enhancement is due to the synchronous action of the electric field and acoustic shock wave pulses.

[A new concept of the structure of the dual electrical layer on the cell surface under the action of a high concentration electrolyte].

New data are presented describing the characteristics of double electrical layers on the surfaces of cells immersed in high electrolytic solutions. Gel glycosides located at the periphery of halo-forming cells play the key role in forming these structures.