Publications by authors named "M V Encinas"
Bovine tuberculosis (bTB), a global zoonotic disease, causes negative effects on human and animal health. PhoP protein is a key regulator of pathogenic phenotypes in members of the Mycobacterium tuberculosis complex, which includes the causative agent of bTB. Despite extensive research on this protein focused in deciphering its regulatory role, little was explored about it as a diagnostic antigen.
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- Partial nephrectomy is the recommended treatment for kidney tumors smaller than 7 cm, and robot-assisted laparoscopic surgery is a minimally invasive technique offering benefits for complex cases.
- A study analyzed 94 patients who underwent robotic partial nephrectomies from November 2012 to December 2022, examining various factors like patient demographics, tumor size, surgical time, and complications.
- Results showed a median follow-up of 25.3 months, with a low complication rate (19.2%) and effective tumor removal, making robotic surgery a safe choice for treating solid kidney masses.
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- The Sprouty genes (Spry1-4) inhibit receptor tyrosine kinases and play important roles in embryo development and tumor suppression in adults.* -
- Research involving adult-onset triple knockout mice for Spry1, Spry2, and Spry4 shows that while these mice experience various health issues, like weight loss and endocrine abnormalities, they do not have an increased incidence of tumors compared to normal mice.* -
- Findings suggest that the loss of Sprouty genes may impact metabolic and endocrine functions without necessarily leading to tumor development.*
Ante-mortem diagnosis of bovine tuberculosis (bTB) is based mainly on the tuberculin skin test (TST) and the ɣ-IFN release assay (IGRA). Some infected animals escape screening tests, thus, limit herd sanitation. Previous reports have suggested a predominant pattern of multi-organ lesions attributable to (the causative agent of bTB) bacteraemia.
View Article and Find Full Text PDFGenes of the Sprouty family (Spry1-4) restrain signaling by certain receptor tyrosine kinases. Consequently, these genes participate in several developmental processes and function as tumor suppressors in adult life. Despite these important roles, the biology of this family of genes still remains obscure.
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