[Free amino acids in brain tissue and its subcellular structures in hyperthermia in rats].

Free amino acids reserves in the brain tissue, nuclei and mitochondria were investigated in mongrel albino rats under conditions of hyperthermia (45 degrees C) of different duration--7,20 and 60 min. It was found that reserves of most free amino acids in the albino rat brain decreased under a short-term (7 min) hyperthermia and accumulated under more prolonged (20-60 min) one. The amount of amino acids in the brain mitochondria increased 7 min after the experiment start and decreased 20 min later, then (60 min later) the amount of most amino acids increased considerably.

[Distribution of free amino acids in the rat brain during ontogenesis].

Distribution of free amino acids reserves in the brain tissues, nuclei and mitochondria of rats is studied in ontogenesis dynamics. It is established that the content of most amino acids in tissues and mitochondria increases by the 6-month age, lowers in the brain tissues and subcellular structures by the 12-month age, decreases in the tissues and nuclei and grows in mitochondria of old animals. The reasons of disbalance in distribution of the reserves of free amino acids are under discussion.

[Dynamics of free amino acids in rat brain tissue during hypothermia].

A comparative study is conducted for the effect of one-, three- and six-hour artificial deep (20-19 degrees C) hypothermia on the content of free amino acids in the blood serum, tissue, nuclei and mitochondria of the rat brain. It is found out that the content is the highest in the blood serum after a three-hour cooling. In the brain tissue the amount of amino acids lowers, especially under conditions of a six-hour hypothermia.

[Dynamics of the content of free amino acids in the liver and serum of rats during ontogenesis].

Dynamics of free amino acid reserves in newborn 3, 6, 12 and 24-month rats was studied in ontogenesis. At all stages of postnatal life they get distributed differently in the liver and blood serum. Both individual and common peculiarities of amino acidic reserve distribution are marked.